diff --git a/smoldyn-use_boost169.patch b/smoldyn-use_boost169.patch
new file mode 100644
index 0000000..2557f9c
--- /dev/null
+++ b/smoldyn-use_boost169.patch
@@ -0,0 +1,7 @@
+--- CMakeLists.orig.txt	2020-05-25 11:24:42.754220000 +0200
++++ CMakeLists.txt	2020-05-25 11:25:53.945372024 +0200
+@@ -430,3 +430,3 @@
+ 
+-    set(Boost_INCLUDE_DIR ${INCLUDE_INSTALL_DIR}/boost)
++    set(Boost_INCLUDE_DIR ${INCLUDE_INSTALL_DIR}/boost169/boost)
+     include_directories(SYSTEM ${Boost_INCLUDE_DIR})
diff --git a/smoldyn.spec b/smoldyn.spec
index 1be0878..391c039 100644
--- a/smoldyn.spec
+++ b/smoldyn.spec
@@ -15,7 +15,7 @@
 Name:  smoldyn
 Summary: A particle-based spatial stochastic simulator
 Version: 2.61
-Release: 1%{?dist}
+Release: 2%{?dist}
 
 # The rxnparam.c and SurfaceParam.c source code files are in the public domain.
 #
@@ -34,7 +34,8 @@ Source0: %{url}/%{name}-%{version}.zip
 Patch0: %{name}-fix_libpaths.patch
 Patch1: %{name}-freeglut.patch
 
-BuildRequires: boost-devel
+Patch2: %{name}-use_boost169.patch
+
 BuildRequires: cmake3
 BuildRequires: gcc
 BuildRequires: %{?dts}gcc-c++
@@ -42,6 +43,9 @@ BuildRequires: %{?dts}gcc-c++
 BuildRequires: %{?dts}toolchain, %{?dts}libatomic-devel
 BuildRequires: boost169-devel
 %endif
+%if 0%{?fedora} || 0%{?rhel} > 7
+BuildRequires: boost-devel
+%endif
 BuildRequires: freeglut-devel
 BuildRequires: libXmu-devel
 BuildRequires: libXi-devel
@@ -94,6 +98,9 @@ BuildArch: noarch
 %if 0%{?fedora}
 %patch1 -p0 -b .freeglut
 %endif
+%if 0%{?rhel} && 0%{?rhel} == 7
+%patch2 -p0 -b .use_boost169
+%endif
 
 # Copy license file
 mv source/lib/SFMT/LICENSE.txt source/lib/SFMT/SFMT-LICENSE.txt
@@ -178,6 +185,9 @@ popd
 %doc documentation/*
 
 %changelog
+* Mon May 25 2020 Antonio Trande <sagitter@fedoraproject.org> - 2.61-2
+- Patched for using Boost169 on EPEL7
+
 * Sun May 24 2020 Antonio Trande <sagitter@fedoraproject.org> - 2.61-1
 - Release 2.61