diff --git a/lldb.spec b/lldb.spec
index f30c152..ede01d7 100644
--- a/lldb.spec
+++ b/lldb.spec
@@ -32,6 +32,13 @@ BuildRequires:	multilib-rpm-config
 
 Requires:	python3-lldb
 
+# s390x build otherwise fails with:
+#In file included from source/Plugins/Process/Linux/NativeRegisterContextLinux_s390x.cpp:21:
+#/usr/include/linux/uio.h:17:8: error: redefinition of 'struct iovec'
+#   17 | struct iovec
+#      |        ^~~~~
+Patch0:		remove-uio-include.patch
+
 # For origin certification
 BuildRequires:	gnupg2
 
diff --git a/remove-uio-include.patch b/remove-uio-include.patch
new file mode 100644
index 0000000..55d50ff
--- /dev/null
+++ b/remove-uio-include.patch
@@ -0,0 +1,12 @@
+diff -ruN lldb-14.0.5.src.orig/source/Plugins/Process/Linux/NativeRegisterContextLinux_s390x.cpp lldb-14.0.5.src/source/Plugins/Process/Linux/NativeRegisterContextLinux_s390x.cpp
+--- a/lldb-14.0.5.src.orig/source/Plugins/Process/Linux/NativeRegisterContextLinux_s390x.cpp	2022-06-10 16:47:36.000000000 +0200
++++ b/lldb-14.0.5.src/source/Plugins/Process/Linux/NativeRegisterContextLinux_s390x.cpp	2022-06-20 14:28:03.551079680 +0200
+@@ -18,7 +18,7 @@
+ 
+ #include "Plugins/Process/Utility/RegisterContextLinux_s390x.h"
+ 
+-#include <linux/uio.h>
++//#include <linux/uio.h>
+ #include <sys/ptrace.h>
+ 
+ using namespace lldb_private;