diff --git a/nauty-popcnt.patch b/nauty-popcnt.patch
index b158d2d..173e77b 100644
--- a/nauty-popcnt.patch
+++ b/nauty-popcnt.patch
@@ -2042,7 +2042,7 @@ Last-Update: 2020-05-21
 +#ifndef __GNUC__
 +#error Runtime popcount support is only available with GCC.
 +#endif
-+#if __GNUC__ < 4 || (__GNUC__ == 4 && __GNUC_MINOR__ < 6)
++#if !__clang__ && (__GNUC__ < 4 || (__GNUC__ == 4 && __GNUC_MINOR__ < 6))
 +#error Runtime popcount support is only available with GCC 4.6 or later.
 +#endif
 +#include <cpuid.h>
diff --git a/nauty.spec b/nauty.spec
index 7f167d6..859bdb2 100644
--- a/nauty.spec
+++ b/nauty.spec
@@ -3,7 +3,7 @@
 
 Name:           nauty
 Version:        %(tr r . <<< %{nautybasever})
-Release:        2%{?dist}
+Release:        3%{?dist}
 Summary:        Graph canonical labeling and automorphism group computation
 
 License:        ASL 2.0
@@ -128,6 +128,9 @@ LD_LIBRARY_PATH=$PWD/.libs make check
 %{_libdir}/pkgconfig/%{name}.pc
 
 %changelog
+* Tue Jan 05 2021 Timm Bäder <tbaeder@redhat.com> - 2.7.1-3
+- Enable runtime popcount support on clang
+
 * Tue Jul 28 2020 Fedora Release Engineering <releng@fedoraproject.org> - 2.7.1-2
 - Rebuilt for https://fedoraproject.org/wiki/Fedora_33_Mass_Rebuild