diff --git a/python-cypari2-python310.patch b/python-cypari2-python310.patch
new file mode 100644
index 0000000..5e5f9b4
--- /dev/null
+++ b/python-cypari2-python310.patch
@@ -0,0 +1,28 @@
+--- cypari2/convert.pyx.orig	2020-11-01 11:52:56.000000000 -0700
++++ cypari2/convert.pyx	2020-11-15 09:35:18.481436232 -0700
+@@ -59,7 +59,7 @@ cdef extern from *:
+     ctypedef struct PyLongObject:
+         digit* ob_digit
+ 
+-    Py_ssize_t* Py_SIZE_PTR "&Py_SIZE"(object)
++    void __Pyx_SET_SIZE(object, Py_ssize_t)
+ 
+ 
+ ########################################################################
+@@ -450,13 +450,11 @@ cdef PyLong_FromINT(GEN g):
+         if d:
+             sizedigits_final = i+1
+ 
+-    # Set correct size (use a pointer to hack around Cython's
+-    # non-support for lvalues).
+-    cdef Py_ssize_t* sizeptr = Py_SIZE_PTR(x)
++    # Set correct size
+     if signe(g) > 0:
+-        sizeptr[0] = sizedigits_final
++        __Pyx_SET_SIZE(x, sizedigits_final)
+     else:
+-        sizeptr[0] = -sizedigits_final
++        __Pyx_SET_SIZE(x, -sizedigits_final)
+ 
+     return x
+ 
diff --git a/python-cypari2.spec b/python-cypari2.spec
index 7ed5e57..ca9c271 100644
--- a/python-cypari2.spec
+++ b/python-cypari2.spec
@@ -3,7 +3,7 @@
 
 Name:		python-%{modname}
 Version:	2.1.2
-Release:	0.1.%{prerel}%{?dist}
+Release:	0.2.%{prerel}%{?dist}
 Summary:	A Python interface to the number theory library pari
 License:	GPLv2+
 URL:		https://github.com/sagemath/%{modname}
@@ -12,6 +12,9 @@ Source0:	https://github.com/sagemath/%{modname}/archive/%{version}%{?prerel}/%{m
 Patch0:		%{name}-pari.patch
 # Fix building with cython language level 3
 Patch1:		%{name}-cython.patch
+# Adapt to python 3.10
+# https://github.com/sagemath/cypari2/pull/103
+Patch2:		%{name}-python310.patch
 
 BuildRequires:	gcc
 BuildRequires:	gmp-devel
@@ -99,6 +102,9 @@ export PATH PYTHONPATH
 %{_docdir}/%{name}/html
 
 %changelog
+* Mon Nov 16 2020 Jerry James <loganjerry@gmail.com> - 2.1.2-0.2.b1
+- Add -python310 patch to adapt to python 3.10
+
 * Mon Nov  9 2020 Jerry James <loganjerry@gmail.com> - 2.1.2-0.1.b1
 - Update to 2.1.2b1 for pari 2.13.0 support
 - Drop upstreamed -literal-block patch