diff --git a/setup.py b/setup.py
index 1a1fe29..65ae2ef 100644
--- a/setup.py
+++ b/setup.py
@@ -12,9 +12,7 @@ install_requires = [
     'cryptography>=0.8',
     # Connection.set_tlsext_host_name (>=0.13)
     'PyOpenSSL>=0.13',
-    # For pkg_resources. >=1.0 so pip resolves it to a version cryptography
-    # will tolerate; see #2599:
-    'setuptools>=1.0',
+    'setuptools',
     'six>=1.9.0',  # needed for python_2_unicode_compatible
 ]