diff --git a/python-pyvex.spec b/python-pyvex.spec
index 43b865a..f26c49d 100644
--- a/python-pyvex.spec
+++ b/python-pyvex.spec
@@ -1,7 +1,7 @@
 %global srcname pyvex
 
 # Has arch-specific dependencies, so cannot build as noarch.
-ExcludeArch: ppc64le
+ExcludeArch: ppc64le s390x
 %global debug_package %{nil}
 
 Name:           python-%{srcname}