diff --git a/USD-21.11-disable-malloc-hooks.patch b/USD-21.11-disable-malloc-hooks.patch
new file mode 100644
index 0000000..e9164cb
--- /dev/null
+++ b/USD-21.11-disable-malloc-hooks.patch
@@ -0,0 +1,23 @@
+diff -Naur USD-21.11-original/pxr/base/arch/mallocHook.cpp USD-21.11/pxr/base/arch/mallocHook.cpp
+--- USD-21.11-original/pxr/base/arch/mallocHook.cpp	2021-11-01 13:10:51.000000000 -0400
++++ USD-21.11/pxr/base/arch/mallocHook.cpp	2022-03-31 17:26:22.176739670 -0400
+@@ -177,7 +177,7 @@
+        _underlyingMemalignFunc || _underlyingFreeFunc;
+ }
+ 
+-#if defined(ARCH_OS_LINUX)
++#if 0
+ template <typename T>
+ static bool _GetSymbol(T* addr, const char* name, string* errMsg) {
+     if (void* symbol = dlsym(RTLD_DEFAULT, name)) {
+@@ -241,8 +241,8 @@
+     ARCH_UNUSED_ARG void  (*freeWrapper)(void*, const void*),
+     string* errMsg)
+ {
+-#if !defined(ARCH_OS_LINUX)
+-    *errMsg = "ArchMallocHook functionality not implemented for non-linux systems";
++#if 1
++    *errMsg = "ArchMallocHook functionality not implemented";
+     return false;
+ #else
+     if (IsInitialized()) {
diff --git a/usd.spec b/usd.spec
index e43eb48..1fab300 100644
--- a/usd.spec
+++ b/usd.spec
@@ -6,9 +6,7 @@
 %bcond_with     documentation
 %bcond_without  embree
 %bcond_without  imaging
-# We must keep jemalloc enabled to work around
-# https://github.com/PixarAnimationStudios/USD/issues/1592.
-%bcond_without  jemalloc
+%bcond_with     jemalloc
 %bcond_with     openshading
 %bcond_with     openvdb
 %bcond_with     ocio
@@ -72,6 +70,12 @@ Patch2:         USD-21.08-OpenEXR3.patch
 # https://github.com/PixarAnimationStudios/USD/pull/1676
 Patch3:         1676.patch
 
+# USD uses deprecated malloc hooks removed in glibc 2.34
+# https://github.com/PixarAnimationStudios/USD/issues/1592
+# Based on:
+# https://github.com/PixarAnimationStudios/USD/issues/1592#issuecomment-1047152905
+Patch4:         USD-21.11-disable-malloc-hooks.patch
+
 # Base
 BuildRequires:  boost-devel
 BuildRequires:  boost-program-options