diff --git a/.gitignore b/.gitignore
index ba6b939..3f69983 100644
--- a/.gitignore
+++ b/.gitignore
@@ -13,3 +13,4 @@ workrave-1.9.1.tar.gz
 /workrave-v1_10_44.tar.gz
 /workrave-v1_10_45.tar.gz
 /workrave-v1_10_49.tar.gz
+/workrave-v1_10_50.tar.gz
diff --git a/578180d0982dd8f0dbe72574ae4758e6903691bb.patch b/578180d0982dd8f0dbe72574ae4758e6903691bb.patch
new file mode 100644
index 0000000..91aa3a2
--- /dev/null
+++ b/578180d0982dd8f0dbe72574ae4758e6903691bb.patch
@@ -0,0 +1,23 @@
+From 578180d0982dd8f0dbe72574ae4758e6903691bb Mon Sep 17 00:00:00 2001
+From: Rob Caelers <rob.caelers@gmail.com>
+Date: Wed, 24 Aug 2022 19:31:37 +0200
+Subject: [PATCH] Support GNOME Shell 43
+
+# Conflicts:
+#	frontend/applets/gnome-shell/src/metadata.json.in
+---
+ frontend/applets/gnome-shell/src/metadata.json.in | 1 +
+ 1 file changed, 1 insertion(+)
+
+diff --git a/frontend/applets/gnome-shell/src/metadata.json.in b/frontend/applets/gnome-shell/src/metadata.json.in
+index 7070a1987..7f55d7a76 100644
+--- a/frontend/applets/gnome-shell/src/metadata.json.in
++++ b/frontend/applets/gnome-shell/src/metadata.json.in
+@@ -26,6 +26,7 @@
+                        "40",
+                        "41",
+                        "42",
++                       "43",
+                        "@shell_current@" ],
+  "localedir": "@LOCALEDIR@",
+  "url": "@url@"
diff --git a/sources b/sources
index e1982f4..45d2d7f 100644
--- a/sources
+++ b/sources
@@ -1 +1 @@
-SHA512 (workrave-v1_10_49.tar.gz) = 9e6d3b73b513139e444fccfbf6fcc45b495df3a43b86369a7a0d4b83c37c98bcdcce1452bc82d956230836038c09f96ea6d2da2dbeac64abd9ace620eace771b
+SHA512 (workrave-v1_10_50.tar.gz) = ccc985518aab06e31447ac9a16f4a39dfae077be581706b4ac88392e4d5e993f32b2bdc5697d7540785d5ebd6f1d31339d5dc1a5f7b6241da44a4e61cce021da
diff --git a/workrave.spec b/workrave.spec
index 1fd2d6a..d02f21f 100644
--- a/workrave.spec
+++ b/workrave.spec
@@ -1,16 +1,18 @@
-%global	gnome_flashback	0
+%global	gnome_flashback	1
 %global	mate		1
 %global	xfce		1
 
 Name: workrave
-Version: 1.10.49
-Release: 3%{?dist}
+Version: 1.10.50
+Release: 1%{?dist}
 Summary: Program that assists in the recovery and prevention of RSI
 # Based on older packages by Dag Wieers <dag@wieers.com> and Steve Ratcliffe
 License: GPLv3+
 URL: http://www.workrave.org/
 %global tag %(echo %{version} | sed -e 's/\\./_/g')
 Source0: https://github.com/rcaelers/workrave/archive/v%{tag}/%{name}-v%{tag}.tar.gz
+# Support GNOME Shell 43, backport of https://github.com/rcaelers/workrave/pull/430
+Patch0:  578180d0982dd8f0dbe72574ae4758e6903691bb.patch
 
 Obsoletes: %{name}-gtk2 < 1.10.37-1
 Provides: %{name}-gtk2 = %{?epoch:%{epoch}:}%{version}-%{release}
@@ -44,7 +46,7 @@ BuildRequires: intltool
 BuildRequires: autoconf, automake, libtool, autoconf-archive
 BuildRequires: desktop-file-utils
 %if 0%{?gnome_flashback}
-BuildRequires: pkgconfig(libpanel-applet)
+BuildRequires: pkgconfig(libgnome-panel)
 %endif
 %if 0%{?xfce} || 0%{?mate}
 BuildRequires: pkgconfig(gtk+-3.0)
@@ -98,6 +100,7 @@ This package provides an applet for the Xfce panel.
 
 %prep
 %setup -q -n workrave-%{tag}
+%patch0 -p1
 touch ChangeLog
 # https://bugzilla.redhat.com/show_bug.cgi?id=304121
 sed -i -e '/^DISTRIBUTION_HOME/s/\/$//' frontend/gtkmm/src/Makefile.*
@@ -187,10 +190,7 @@ desktop-file-install \
 
 %if 0%{?gnome_flashback}
 %files gnome-flashback
-%{_libexecdir}/gnome-applets/workrave-applet
-%{_datadir}/dbus-1/services/org.gnome.panel.applet.WorkraveAppletFactory.service
-%{_datadir}/gnome-panel/5.0/applets/org.workrave.WorkraveApplet.panel-applet
-%{_datadir}/gnome-panel/ui/workrave-gnome-applet-menu.xml
+%{_libdir}/gnome-panel/modules/libworkrave-applet.so
 %endif
 
 %if 0%{?xfce}
@@ -208,6 +208,11 @@ desktop-file-install \
 %endif
 
 %changelog
+* Fri Nov 04 2022 Yaakov Selkowitz <yselkowi@redhat.com> - 1.10.50-1
+- Update to 1.10.50
+- Enable GNOME Flashback applet
+- Support GNOME Shell 42 (#2132504) and 43 (#2132507)
+
 * Sat Jul 23 2022 Fedora Release Engineering <releng@fedoraproject.org> - 1.10.49-3
 - Rebuilt for https://fedoraproject.org/wiki/Fedora_37_Mass_Rebuild