diff -up zabbix-6.0.2/ui/include/classes/core/CConfigFile.php.config zabbix-6.0.2/ui/include/classes/core/CConfigFile.php
--- zabbix-6.0.2/ui/include/classes/core/CConfigFile.php.config	2022-03-23 08:38:25.049013803 -0600
+++ zabbix-6.0.2/ui/include/classes/core/CConfigFile.php	2022-03-23 08:39:25.001657019 -0600
@@ -25,7 +25,7 @@ class CConfigFile {
 	const CONFIG_ERROR = 2;
 	const CONFIG_VAULT_ERROR = 3;
 
-	const CONFIG_FILE_PATH = '/conf/zabbix.conf.php';
+	const CONFIG_FILE_PATH = '/etc/zabbix/web/zabbix.conf.php';
 
 	private static $supported_db_types = [
 		ZBX_DB_MYSQL => true,
diff -up zabbix-6.0.2/ui/include/classes/core/ZBase.php.config zabbix-6.0.2/ui/include/classes/core/ZBase.php
--- zabbix-6.0.2/ui/include/classes/core/ZBase.php.config	2022-03-14 03:57:00.000000000 -0600
+++ zabbix-6.0.2/ui/include/classes/core/ZBase.php	2022-03-23 08:38:25.052013836 -0600
@@ -368,7 +368,7 @@ class ZBase {
 	 * @throws Exception
 	 */
 	protected function setMaintenanceMode() {
-		require_once 'conf/maintenance.inc.php';
+		require_once '/etc/zabbix/web/maintenance.inc.php';
 
 		if (defined('ZBX_DENY_GUI_ACCESS')) {
 			if (!isset($ZBX_GUI_ACCESS_IP_RANGE) || !in_array(CWebUser::getIp(), $ZBX_GUI_ACCESS_IP_RANGE)) {
@@ -381,7 +381,7 @@ class ZBase {
 	 * Load zabbix config file.
 	 */
 	protected function loadConfigFile() {
-		$configFile = $this->getRootDir().CConfigFile::CONFIG_FILE_PATH;
+		$configFile = CConfigFile::CONFIG_FILE_PATH;
 		$config = new CConfigFile($configFile);
 		$this->config = $config->load();
 	}
diff -up zabbix-6.0.2/ui/include/classes/setup/CSetupWizard.php.config zabbix-6.0.2/ui/include/classes/setup/CSetupWizard.php
--- zabbix-6.0.2/ui/include/classes/setup/CSetupWizard.php.config	2022-03-14 03:57:00.000000000 -0600
+++ zabbix-6.0.2/ui/include/classes/setup/CSetupWizard.php	2022-03-23 08:38:25.054013857 -0600
@@ -271,7 +271,7 @@ class CSetupWizard extends CForm {
 				// make zabbix.conf.php downloadable
 				header('Content-Type: application/x-httpd-php');
 				header('Content-Disposition: attachment; filename="'.basename(CConfigFile::CONFIG_FILE_PATH).'"');
-				$config = new CConfigFile(APP::getInstance()->getRootDir().CConfigFile::CONFIG_FILE_PATH);
+				$config = new CConfigFile(CConfigFile::CONFIG_FILE_PATH);
 				$config->config = [
 					'DB' => [
 						'TYPE' => $this->getConfig('DB_TYPE'),