diff -rupN Python-2.7.14/setup.py Python-2.7.14-new/setup.py
--- Python-2.7.14/setup.py	2017-10-31 18:36:37.848181685 +0100
+++ Python-2.7.14-new/setup.py	2017-10-31 18:36:38.951181402 +0100
@@ -463,7 +463,8 @@ class PyBuildExt(build_ext):
             add_dir_to_list(self.compiler.include_dirs, '/usr/local/include')
         if cross_compiling:
             self.add_gcc_paths()
-        self.add_multiarch_paths()
+        if not cross_compiling:
+            self.add_multiarch_paths()
 
         # Add paths specified in the environment variables LDFLAGS and
         # CPPFLAGS for header and library files.